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Tsai Laboratory

Our laboratory seeks to advance diagnostic hematopathology using next generation immunophenotyping. This work combines: 1. practical experience clinically diagnosing human tissue, 2. operational knowledge of mass cytometry/cytometry by time-of-flight (CyTOF) and multiplexed ion beam imaging (MIBI), and 3. fundamental discoveries in the biology of dysplasia/neoplasia. Combining this with an understanding of clinical laboratory testing, we aim to bring these techniques into routine clinical diagnostics.

Our current focus is myelodysplastic syndrome (MDS) — an especially complex and heterogeneous disease of abnormal blood cell development with increasing prevalence and few treatments, which particularly benefits from single cell approaches.

Tsai Laboratory

Our laboratory seeks to advance diagnostic hematopathology using next generation immunophenotyping. This work combines: 1. practical experience clinically diagnosing human tissue, 2. operational knowledge of mass cytometry/cytometry by time-of-flight (CyTOF) and multiplexed ion beam imaging (MIBI), and 3. fundamental discoveries in the biology of dysplasia/neoplasia. Combining this with an understanding of clinical laboratory testing, we aim to bring these techniques into routine clinical diagnostics.

Our current focus is myelodysplastic syndrome (MDS) — an especially complex and heterogeneous disease of abnormal blood cell development with increasing prevalence and few treatments, which particularly benefits from single cell approaches.